A New Asthma Research Could Be a Possible Breakthrough for Better Treatment

A New Asthma Research Could Be a Possible Breakthrough for Better Treatment ...

Scientists have made an important finding that may lead to improved asthma care for individuals with severe asthma disorders. The research, published in the European Respiratory Journal, is part of a larger pan-European collaboration investigating asthma and its different subtypes.

Dr Stacey Reinke (ECU) and Dr Craig Wheelock (Karolinska Institute, Sweden) conducted a research that found that severe asthmatics had reduced levels of carnitines, a specific type of metabolite. Carnitines are a major component of the body's cellular energy generation process as well as the immune response.

Researchers hope that the breakthrough will help develop better treatment strategies. Severe asthma occurs when someone's asthma is uncontrolled, despite being treated with high doses of medication or multiple medications. We first need to understand the disease's mechanisms, according to Dr. Reinke.

One of the problems with asthma research is the difficulty of researchers investigating the lungs directly. Using invasive procedures, it becomes difficult for scientists to examine what is going on inside the lungs. However, scientists may be able to examine the distribution of blood that travels through the lungs, which are then excreted from the urine.

Dr Reinke suggested that using the urinary metabolome of asthmatics we were able to find fundamental differences in energy metabolism that might be a target for future asthma control strategies.

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