Blood Pressure is constantly decreased as a result of Deep Nerve stimulation

Blood Pressure is constantly decreased as a result of Deep Nerve stimulation ...

A biomedical engineer at the University of Houston is expanding the research of wireless electrodes in order to treat hypertension and is reporting that bioelectronic therapy is used to control blood pressure and renal sympathetic nerve activity (RSNA). In addition to hypertension and renal disease, the number of applications is increased.

Mario Romero-Ortega, a Cullen-Endowed Professor of Biomedical Engineering, previously claimed that deep peroneal nerve stimulation (DPNS) induces an acute blood pressure. The present study, focused on his development of a small implantable wireless neural stimulation system and his exploration of various stimulation parameters to achieve a maximum lowered response, has been published inFrontiers in Neuroscience.

Romero-Ortega incorporated a sub-millimeter nerve stimulation circuit with a novel nerve attachment microchannel electrode that facilitates implantation into small nerves and facilitates external power and DPNS modulation control.

After nerve stimulation, his team tested that systolic blood pressure may be reduced by 10% in one hour and 16% two hours.

According to Romero-Ortega, DPNS consistently induces an immediate and reproducible arterial depressor effect as a result of electrical stimulation of the deep peroneal nerve.

Hypertension, often known as the silent killer, speaks loudly in statistics. In the United States, it is the number one cause of death. Globally it is the number one risk factor for death, which affects more than half of all stroke and heart related deaths. The American College of Cardiology/American Heart Association 2018 guidelines classified average systolic blood pressure as greater than 130 mmHg and diastolic BP greater than 80 mmHg on at least two occasions, as hypertension.

Despite the use of several antihypertensive medicines in combination, blood pressure remains poorly controlled in 5060% of hypertensive individuals, and approximately 1218 percent of these individuals develop resistance hypertension. Blood pressure is defined as as blood pressure greater than 140/90 mg/kg, despite the use of antihypertensive drugs.

Despite the increase in heart rate, DPNS induced an initial increase in RSNA in the first 23 seconds, followed by a decrease in renal activity and mean arterial pressure.

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