Andrew Taylor, Ph.D., Services Technical Support ManagerThis mini-webinar explains why transporters are responsible for absorption, distribution, tissue-specific drug targeting, and eliminating drugs. These include, among others, transporters who have been involved in many drugdrug interactions. These include, for example, transporters that have been involved in many of the movement of a compound through the body.
- An overview of drug transporters, including ATP-binding cassette (ABC) and solute carrier (SLC)
- Why drug transporter studies are important, including a real-world example
- An explanation of transporter expression and function
- Regulatory guidance on transporters, including FDA, EMA & PMDA
- Inhibition and substrate transporter study design, including Efflux Transporter Transwell Assays, SLC Transporter Uptake Assays, and BSEP and MRP2 Vesicle Assays
- An example of study result data
- Different transporter study and test system options and more
Download slides: https://www.xenotech.com/webinar-slides/sekisui-xenotech_drug-transport-adme-101.pdfQuestions, comments, and requests: https://www.xenotech.com/contact-usMore information on our research services and test systems: https://www.xenotech.com/newsletter-signupRequest a webinar topic: https://www.xenotech.
Dr. Andrew G. Taylor, who works as a research scientist at SEKISUI XenoTech in 2017, completing the OECD Principles of GLP and/or Japan MOHW GLP standards, and providing valuable guidance to ensure research needs are met.