Measuring BMI in a New Way Is Possible To Identify Obesity Risk

Measuring BMI in a New Way Is Possible To Identify Obesity Risk ...

Obesity and excess weight increase the risk of developing type 2 diabetes, but individuals with normal weight may also develop the disease. Researchers at Lund University in Sweden have discovered that metabolic changes linked with obesity have heightened the likelihood of developing type 2 diabetes.

Type 2 diabetes is a connection to a sedentary lifestyle that leads to excessive weight and obesity. Up to 20 percent of type 2 diabetes patients are obese, and it is important to identify individuals in this group who are at danger.

A broad spectrum of researchers has been asked if it is possible to identify them by studying the levels of several of the metabolic factors that are relevant for metabolism.

According to Filip Ottosson, the author of the Diabetes Care study, we identified a group of individuals with regular BMI who did not experience metabolic changes related to obesity in their metabolism.

In blood samples from 7663 participants in three populations in Sweden and Italy, they were classified into five groups based on their metabolic BMI. Individuals with a metabolic BMI five BMI units higher than their BMI based on height and weight were examined further. This group had a twofold risk of developing type 2 diabetes compared to individuals with a regular BMI.

Olle Melander, a professor of internal medicine at Lund University, is one of the authors of the study. We hope that our research will be used to identify individuals with a hidden risk of developing the disease. If we can identify these individuals before the disease develops, we might be able to initiate preventive actions. This may, however, save society a lot of money as type 2 diabetes often leads to a range of consequences.

The research team used machine learning techniques to classify participants with different metabolic profiles to estimate the risk for type 2 diabetes. Participants then followed up participants who developed type 2 diabetes in the population-based Malmo Diet Cancer (MDC) cohort in Sweden, which has a follow-up time of 20 years. The results will need to be verified in other cohorts, and further research is also required.

This may be a new approach for screening for type 2 diabetes and for initiating preventive measures for people with normal weight that are at high risk of developing the disease. However, this group will not benefit, which implies alternative interventions. According to Filip Ottosson, in the long-term perspective, we may develop medicines that would lower the levels of some of the metabolites.

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