Sartorius has introduced the Octet SF3, the first Surface Plasmon Resonance (SPR) system under the Sartorius Octet brand. Up until now, the Octet name has been synonymous with Bio-Layer Interferometry (BLI), a proprietary fluidic-free instrument platform for real-time, label-free biomolecular interactions. This partnership establishes Sartorius as the only company to provide customers with the two leading label technologies, BLI and SPR, under
Sartorius continues to push the boundaries of innovation within the label-free protein analysis market, according to Dr. Darius Wilson, the product manager at BioAnalytics Workflows. Researchers now have two established leading technologies under a single brand they both know and trust.
The Octet SF3 is a next-generation SPR instrument that allows customers to achieve high baseline noise and drift, with significant injection volumes and innovative injection techniques, allowing users to produce high-quality kinetics and affinity data in fractions of the time. Both frequent and infrequent SPR users are able to answer any question thanks to its combination of engineering design and intuitive software.
The Octet SF3 is a combination of powerful hardware capabilities, including high sensitivity, extended dissociation times, and more than 72 hours of unattended run-time, according to Darius. However, the power of the Octet SF3 is not only limited to individual hardware features, but also its diverse range of injection types that cover all research applications, making this system truly unique.
The Octet SF3 is powered and ready for all research applications and assays, from industry standard multi-cycle kinetics to the patented OneStep, Onestep Two Comp, OneStep Pulse, and NeXtStep Gradient Injections. The OneStep Injection Technology eliminates the need to create a multiple dilution series, allowing users to create a comprehensive concentration gradient for kinetics and affinity testing by utilizing only one analyte solution.
According to Darius, all compounds may behave differently depending on specific stress conditions. It is therefore crucial that any SPR platform has the capability to accurately assess these differences in the least complicated and time-consuming manner possible, compared to the Octet SF3 as shown in ease of use.
Keeping pace with the growing demand for antibody fragment characterization, vaccination research, and biologics discovery, BLI and SPR have dominated as the two robust methods for characterizing biomolecular interactions in a variety of applications. The Sartorius Octet platform, which is label-free, is taking the lead by providing customers with both solutions under the brand they have now become dependent on.