In a new study, the link between excessive napping and Alzheimer's disease was discussed

In a new study, the link between excessive napping and Alzheimer's disease was discussed ...

A link between cognitive decline and excessive daytime napping is possible, according to a new research from the Rush Alzheimers Disease Center. An article published inAlzheimers and Dementia: The Alzheimers Associationin March

Researchers believe that the connection between the two directions appears to be significant. After one year, longer and more frequent napping was correlated with worse cognition, and worse cognition was correlated with longer and more frequent napping.

Aron Buchman, a neurologist at Rush University Medical Center and author of the article, claims that the research exposes the evolving view ofAlzheimers diseaseas as a pure cognitive disorder.

We now know that the pathology relating to cognitive decline might avert other changes in function, he added. Its really a multi-system disorder, with such issues as difficulty sleeping, movement, changes in body composition, depression symptoms, behavioral changes.

As part of the RushMemory and Aging Projectand theReligious Order Study, researchers tracked 1,400 patients for up to 14 years. Participants wore a wrist-worn sensor that recorded activity continuously for up to 10 days, and came in once a year for testing and cognitive testing. Any prolonged period of no activity during the daytime from 9 a.m. to 7 p.m. was considered a nap.

According to reports, more than 75 percent of participants showed no signs of cognitive impairment, 9.5 percent had mild cognitive impairment, and a slightly more than 4% had Alzheimer''s disease dementia. Naps increased by about 11 minutes per year among those who didn''t develop cognitive impairment during the follow-up.

Researchers compared participants who had moderate cognition at the start of the study, but developed Alzheimer''s disease dementia to their counterparts who remained constant during the study. They found that older individuals who napped more than an hour a day had a 40% higher risk of developing Alzheimer''s.

According to Buchman, the study does not imply that napping is linked to Alzheimersdementia or vice versa.

This is an observational study, so we cant say that a causes b, he said. Nevertheless, we can say that they unfold at the same time, and that each pathologies may benefit from the same effect.

Alzheimers disease is caused by the accumulation of two proteins, amyloid beta and tau, inside the brain. While the decrease in cognitive function is the most well-known cause of Alzheimers disease, this protein accumulation may occur in several locations of the brain, brainstem, and spinal cord, triggering a variety of symptoms. The study suggests that increases in napping frequency and duration may be one of these symptoms.

You may also work on options, according to Buchman. There are proteins or genes that might prevent tau and beta accumulation, or there are other strategies to mitigate or slow their accumulation.

The National Institutes of Health and the BrightFocus Foundation Alzheimers Research Program sponsored this research. Buchman said that one of the study''s primary strengths was its participant cohorts from the Memory and Aging Project and the Religious Order Study. Both studies are decades-long efforts that require participants to undergo annual testing, sample collecting, and organ donation following their deaths.

People in our research are very special people, according to him. Without people making this kind of contribution, we would not be able to do the research we do. They are so glad to be able to participate, and they animate the staff with their participation. We are very fortunate to have them.

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