A large US study published by The BMJtoday claims that less people have died from covid-19 in better vaccinated communities.
Based on statistics for 2,558 counties in 48 states in the United States, the findings show that counties with high vaccination coverage had a more than 80% reduction in death rates than counties with mostly unvaccinated populations.
This substantial benefit complements the growing body of evidence indicating the possibility of covid-19 vaccination at any given level. A linked editorial argues that encroaching people to keep up with vaccination saves lives.
Over 11 billion covid-19 vaccination doses have been administered worldwide since the 11 April 2022 epidemic, according to the World Health Organizations mission. By the end of 2022, 70% of the world''s population will be vaccinated.
Despite previous vaccination studies, the benefits of scaling up covid-19 vaccination remain evident at the individual level.
Researchers at the US Centers for Disease Control and Prevention (CDC) have devised a strategy to assess how increased county coverage of vaccinations affected population mortality and the incidence of covid-19.
The findings are based on more than 30 million cases of covid-19 and over 400,000 fatalities linked to covid-19 in 2558 counties during the second year of the epidemic, between December 2020 and December 2021.
They compared reported covid-19 incidence and mortality rates in counties with very low (0-9%), low (10-39%), medium (40-69%) and high (70% or greater) vaccination coverage - defined as a percentage of adults (18 and older) who had received at least one dosage of a covid-19 vaccine.
After taking into account potentially beneficial factors, researchers found that increased immunization in towns was linked to a reduction in levels of covid-19 related mortality and instances.
In counties with low, medium, and high vaccination coverage, as a result of the dominant coronavirus in the first half of 2021, the covid-19 mortality rate was reduced by 60%, 75%, and 81% in the first half of 2021, when the alpha variation of coronavirus remained dominant.
The corresponding figures for the reduction in cases were 57%, 70%, and 80%.
During the second half of 2021, the delta variation became dominant in the United States, although smaller effects affected case levels.
This is an observational study that can''t establish the cause, and the researchers argue that several limitations should be considered when interpreting these findings. For example, additional markers of severe disease, such as hospital admissions, were not explored, and they did not control for factors such as rules on wearing a face mask and physical distancing at the time, which may have adverse effects.
They claim that recent sensitivity analyses provided clear findings that they withstand scrutiny. And they claim that future research may benefit from the impact of improved population health, such as increases in employment rates and gross domestic product, as a result of the reopening of society.
In a linked article, Professor Christopher Dye at the University of Oxford reviews the evidence.
According to this study, many more lives might have been saved and will be saved by enforcing people to keep up with vaccinations in the face of decreasing immunity and new coronavirus strains, and by achieving even greater population coverage.
he concludes that life is a challenge for others to study. Gleichzeitig, this new research is another confidence booster for covid-19 vaccinations.