Evonetix has received a patent for technology that allows for a thermally-controlled DNA synthesis

Evonetix has received a patent for technology that allows for a thermally-controlled DNA synthesis ...

EVONETIX LTD (Evonetix), a synthetic biology business that advances semiconductor technology to DNA synthesis, has announced that it has been granted a patent EP3551331B1 in Europe for its proprietary thermal control technology for DNA synthesis as well as the design and manufacture of its silicon chips. This patent extends Evonetix''s IP portfolio and is a key step in the Company''s strategy to develop a benchtop DNA synthesis platform, to transform how DNA is extracted, processed, and used

Evonetix''s new approach to parallel DNA synthesis is backed by a precise, independent, temperature control at tens of individual synthesis sites across the surface of a silicon chip. The thermal control scheme is combined with semiconductor-based arrays, allowing greater precision and selectivity to deprotect sequences at the correct point to add the next nucleotide and eliminate mismatching sequences.

Thermal control of DNA synthesis simplifies highly parallel synthesis and allows it to construct sequences that are difficult to synthesise with conventional techniques, as well as to rectify errors during gene sequence assembly through temperature mediated error removal.

Evonetix''s chief technology officer commented that there is currently an unmet need for long-term DNA sequences in the synthetic biology industry, and that the ability to remove errors during assembly allows researchers to achieve long-term strands of DNA, as well as running applications such as gene synthesis, CRISPR screening, and protein engineering. Adding further strength to our IP portfolio, Evonetix''s position as leading researchers. Our technology will increase the advancement of synthetic biology and further expanding possibilities in this exciting market.

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