SARS-CoV-2 Triggers an Immune Response in the Brain, according to new research

SARS-CoV-2 Triggers an Immune Response in the Brain, according to new research ...

Dr Mayo Olajide, a researcher at the University of Huddersfield, has published a new research describing how the coronavirus''s spike protein enters human cells can have a similar effect on the brains immune cells as it does with the rest of the body.

The HUDDERSFIELD researchers were among the firsttodemonstrate how the induction of brain inflammation caused neurological damage in COVID19 patients and today, their findings have been published in a peer-reviewed medical journal.

The study, published in the journal Molecular Neurobiology by the University of HuddersfieldsDr Mayo Olajide, explains how the coronavirus-like spike protein may have an similar effect on the brains immune cells, as it can affect the rest of the body.

Dr Olajide, who pioneered research on how Alzheimer''s disease can be reduced and some of its symptoms have been affected by a natural compound found in the pomegranate, studied the potential implications of the Spike Glycoprotein S1 using immune cell lines obtained from mice, and is now seeking funding to develop the research further using brain cells from humans.

Dr Olajide claims that following our assumption, we are now questioning when the coronavirus has affected the brain, how might it be a risk for neurodegenerative disorders further down the line, like Alzheimer''s or Parkinson''s?

How the coronavirus activates the brain''s own immune system

Despite other studies, Dr Olajide suggests that althoughthe coronavirus benefited the brain''s own immune response, it was among the first to demonstrate how the virus activated the brain.

It may not be multiplying in the brain, but when it gets into the brain, it can also induce immune responses, and this explains some of the trends people have experienced when they have been infected, such as persistent brain fog and memory loss.

If adequate funding is achieved, Dr Olajide believes the research would be significant.

The problem with COVID research is that many people speculate, but less actually carry out the necessary research to prove their work, because it takes such a long time to complete.

Dr Olajide is a member of the University of Wisconsin''s Pharmacy Department. His academic career includes a postdoctoral research fellowship at the Centre for Drug Research at the University of Munich. After an investigation of the anti-inflammatory properties of natural products, the Dr. Olajide was awarded the University of Ibadan in his native Nigeria.

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