Despite this substantial potential, biomacromolecules are able to enter cells using large biological molecules, which are extremely useful for the treatment of diseases. This discovery, led by Professor Ali Miserez, has proven to be effective in gene therapy, chemotherapy, and vaccination treatment, as well as others. This discovery has brought the University of Singapore to an end, claiming that its large potential has weakened the government''s commitment to innovation.
New delivery system bypasses cell membrane
The researchers synthesised a peptide from a plastic beak to form the microdroplet due to its biological ability to store molecules and low toxicity. Moreover, these molecules, which are made possible by liquid-liquid phase separation (LLPS), are capable of escaping endocytosis, revealing that the cells can safely enter the cell membrane without disrupting the process. These molecules, according to Prof Miserez, have been tested for several years before. These were previously used in experiments to demonstrate that large quantities of
A delivery system for a variety of drugs
peptide droplets are often used to demonstrate the effectiveness of drug carriers, as well as the protein-carb seed. This method was successful in selecting drugs from each other, and it allowed them to enter the cells quicker than previously thought. This method, according to Prof Miserez, has shown that the protein-based cargo is well-known, and therefore is more beneficial to their customers. We recommend that you select a protein from each sample, according to the manufacturer.
The potential future of drug delivery
Several interesting discoveries have been made by the NTU scientists, which includes preparing the peptides into microdroplets and removing them from the cells, indicating that they are capable of performing the same functions as drug carriers. This has paved the way for future research by starting animal investigations this year.