Scientists Have Found A Way To Treat Baldness With Stem Cells
South Korean medical scientists have conducted a clinical study of the effectiveness of treating baldness with a drug derived from proteins secreted by adipose tissue stem cells. The results are published in the journal Stem Cells Translational Medicine.
Adipose tissue stem cells secrete several growth hormones that help cells develop and multiply. Certain growth factors associated with these hormones, such as hepatocyte growth factor, vascular endothelial growth factor, insulin-like growth factor, and platelet growth factor, are known to increase the size of the hair follicle during hair formation and growth.
Researchers from Busan National University decided to test experimentally whether an extract from adipose tissue stem cells will help in the treatment of androgenetic alopecia — the most common type of baldness caused by genetic, hormonal and environmental factors and affecting more than half of all men over 50 years old and almost as many women.
Androgenetic alopecia, although it does not belong to dangerous diseases for human health, adversely affects the psychological state and quality of life of people. There are several approved medications for the treatment of hair loss, but the most effective ones have unpleasant side effects, such as loss of libido and erectile dysfunction. Therefore, scientists continue to search for a safer and more effective treatment.
An extract from adipose tissue stem cells was obtained in the laboratory of Busan University by destroying the stem cell membrane using low-frequency ultrasound waves.
The study involved 38 patients, 29 men and nine middle-aged women with androgenetic alopecia, who were divided into two groups. Representatives of one group rubbed an extract containing adipose stem cells into the scalp twice a day, and participants of the other, a placebo control group.
After 16 weeks, patients using stem cells showed a significant increase in the number of hairs and the diameter of the follicles.
"It is known that adipose stem cells promote hair growth in both men and women, but no randomized, placebo-controlled human study has previously investigated the effects and safety of using adipose stem cell extract for the treatment of alopecia," the press release of the publisher quoted the head of the study, Dr. Sang Yeoup Lee from the family medicine Clinic and the Research Institute for convergence of biomedical Sciences and technologies of Busan National University.
The results of tests show that an extract from adipose tissue stem cells can become a new solution for restoring hair, increasing its density and density, and a safe alternative to existing therapeutic methods, scientists believe.
In the future, the authors plan to conduct similar studies with a large number of participants of different ages and from different population groups.