Updates on Metal Gear Solid 2: Substance have recently been confirmed. However, you may only play it on the emulator PlayStation 2, although keyboard and mouse support is available. User Bl4ckH4nd has many similar projects for classic games.
One of the players has already shown the gameplay of the fan remaster. He used an RTX 4090 graphics card on his desktop, and the game itself was launched in 4K resolution at sixty frames per second.
Igromania: more information